Tate J T, Cowan G S
Am Surg. 1977 Dec;43(12):811-6.
Using intravenous saline as a control, the kinetics of insulin in protein hydrolysate (hyperalimentation) solutions in glass bottles with and without the addition of albumin were studied using double radioisotope tags. Albumin is not a necessary additive to the solution. A technique for providing constant, predictable delivery of insulin is described. Albumin, when added to hyperalimentation and saline solutions with insulin, does not protectively coat plastic tubing or glass bottle surfaces to prevent insulin adsorption; some other mechanism is responsible for the increased insulin concentrations in intravenous solutions with added albumin.
以静脉注射生理盐水作为对照，使用双放射性同位素标记研究了玻璃瓶中添加和未添加白蛋白的蛋白质水解物（胃肠外营养）溶液中胰岛素的动力学。白蛋白并非溶液的必需添加剂。描述了一种实现胰岛素持续、可预测给药的技术。当白蛋白添加到含有胰岛素的胃肠外营养液和生理盐水中时，它不会保护性地覆盖塑料管道或玻璃瓶表面以防止胰岛素吸附；其他一些机制导致添加白蛋白的静脉溶液中胰岛素浓度升高。
