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Editorial Expression of Concern: Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer.

作者信息

Li Yang, Zou Lihua, Li Qiyuan, Haibe-Kains Benjamin, Tian Ruiyang, Li Yan, Desmedt Christine, Sotiriou Christos, Szallasi Zoltan, Iglehart J Dirk, Richardson Andrea L, Wang Zhigang Charles

机构信息

Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.

Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Nat Med. 2025 Dec;31(12):4316. doi: 10.1038/s41591-025-04149-w.

DOI:10.1038/s41591-025-04149-w
PMID:41350453
Abstract
摘要

相似文献

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Editorial Expression of Concern: Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer.
Nat Med. 2025 Dec;31(12):4316. doi: 10.1038/s41591-025-04149-w.
2
Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer.LAPTM4B 和 YWHAZ 的扩增导致乳腺癌的化疗耐药和复发。
Nat Med. 2010 Feb;16(2):214-8. doi: 10.1038/nm.2090. Epub 2010 Jan 24.
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Co-expression of HIF-1α, MDR1 and LAPTM4B in peripheral blood of solid tumors.实体瘤外周血中缺氧诱导因子-1α、多药耐药蛋白1和溶酶体相关跨膜蛋白4B的共表达
PeerJ. 2019 Feb 7;7:e6309. doi: 10.7717/peerj.6309. eCollection 2019.
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LAPTM4B gene copy number gain is associated with inferior response to anthracycline-based chemotherapy in hormone receptor negative breast carcinomas.LAPTM4B 基因拷贝数增加与激素受体阴性乳腺癌对基于蒽环类药物的化疗反应不佳相关。
Cancer Chemother Pharmacol. 2018 Jul;82(1):139-147. doi: 10.1007/s00280-018-3602-z. Epub 2018 May 16.
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Overexpression of LAPTM4B: an independent prognostic marker in breast cancer.LAPTM4B 过表达：乳腺癌的一个独立预后标志物。
J Cancer Res Clin Oncol. 2013 Apr;139(4):661-7. doi: 10.1007/s00432-012-1368-y. Epub 2013 Jan 6.
6
MicroRNA-132-3p inhibits tumor malignant progression by regulating lysosomal-associated protein transmembrane 4 beta in breast cancer.microRNA-132-3p 通过调节乳腺癌中溶酶体相关蛋白跨膜 4β 抑制肿瘤恶性进展。
Cancer Sci. 2019 Oct;110(10):3098-3109. doi: 10.1111/cas.14164. Epub 2019 Aug 19.
7
YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo-/radio-resistance by suppressing caspase-mediated apoptosis.YWHAZ 扩增/过表达定义了侵袭性膀胱癌，并通过抑制半胱天冬酶介导的细胞凋亡来导致化疗/放疗耐药。
J Pathol. 2019 Aug;248(4):476-487. doi: 10.1002/path.5274. Epub 2019 Apr 29.
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Gene Expression and Polymorphism as Diagnostic Markers of Breast Cancer in Egyptian Patients.基因表达与多态性作为埃及乳腺癌患者的诊断标志物
J Med Biochem. 2015 Oct;34(4):393-401. doi: 10.2478/jomb-2014-0067. Epub 2015 Sep 19.
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Prognostic significance of LAPTM4B and p27kip1 expression in triple-negative breast cancer.LAPTM4B 和 p27kip1 表达在三阴性乳腺癌中的预后意义。
Cancer Biomark. 2019;25(1):19-27. doi: 10.3233/CBM-182094.
10
Overexpressed LAPTM4B-35 is a risk factor for cancer recurrence and poor prognosis in non-small-cell lung cancer.过表达的LAPTM4B-35是非小细胞肺癌癌症复发和预后不良的一个风险因素。
Oncotarget. 2016 Aug 30;7(35):56193-56199. doi: 10.18632/oncotarget.10907.

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