Ph1阴性慢性粒细胞白血病中9q+染色体缺失
Absence of the 9q plus chromosome in Ph1 negative chronic myelogenous leukaemia.
作者信息
Rowley J D
出版信息
J Med Genet. 1974 Jun;11(2):166-70. doi: 10.1136/jmg.11.2.166.
Abstract
Bone marrow chromosomes from four patients with Ph negative chronic myelogenous leukaemia have been examined with quinacrine fluorescence. The marrow cells of all four patients showed an apparently normal karyotype. This karyotype is different from that of the Ph positive variant in which a possible translocation (9q+;22q−) has been observed.
摘要
对4例Ph阴性慢性粒细胞白血病患者的骨髓染色体进行了喹吖因荧光检查。所有4例患者的骨髓细胞均显示出明显正常的核型。这种核型与Ph阳性变异型不同，在后者中观察到了一种可能的易位（9q+；22q−）。
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