在冈比亚分离出的沙眼病原体血清型：关于血清型与形态学关系的观察

Serotypes of trachoma agent isolated in the Gambia: with an observation on the relation between serotype and morphology.

作者信息

Sowa J, Collier L H, Sowa S

出版信息

J Hyg (Lond). 1974 Jun;72(3):389-95. doi: 10.1017/s0022172400023627.

DOI:10.1017/s0022172400023627

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2130523/

Abstract

Of 60 TRIC agents isolated from Gambian children with trachoma, 25 were serotype 1 and the remainder type 2. There was a pronounced difference in the proportions of these types in the two villages studied. In the village with a predominance of type 2 strains, TRIC agents remained confined to 2 adjacent compounds over a 14 month observation period. All 19 type 1 strains examined were characterized by the appearance in yolk sac smears of compact aggregates of elementary bodies; such aggregates were seen in only 2 of 35 type 2 strains, and may reflect a chemical difference in the surface of the elementary bodies or in a substance elaborated during their replication.

摘要

从冈比亚患沙眼儿童中分离出的60株沙眼包涵体结膜炎病原体（TRIC）中，25株为血清型1，其余为血清型2。在两个研究村庄中，这些类型的比例存在显著差异。在以血清型2菌株为主的村庄，在14个月的观察期内，TRIC病原体一直局限于相邻的2个居住区。所检测的19株血清型1菌株的特征是，卵黄囊涂片上出现原体紧密聚集体；在35株血清型2菌株中，只有2株出现这种聚集体，这可能反映了原体表面或其复制过程中产生的一种物质的化学差异。

相似文献

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Serotypes of trachoma agent isolated in the Gambia: with an observation on the relation between serotype and morphology.在冈比亚分离出的沙眼病原体血清型：关于血清型与形态学关系的观察

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Relative sensitivity of cell culture and yolk sac for detection of TRIC infection.细胞培养和卵黄囊对检测猪传染性胃肠炎病毒感染的相对敏感性。

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10

A comparison of the iodine and fluorescent antibody methods for staining trachoma inclusions in the conjunctiva.结膜沙眼包涵体染色中碘染色法与荧光抗体法的比较。

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本文引用的文献

1

SEROLOGIC STRAIN DIFFERENTIATION IN TRACHOMA.沙眼的血清学菌株鉴别

J Exp Med. 1964 Oct 1;120(4):639-54. doi: 10.1084/jem.120.4.639.

2

Differentiation of trachoma strains on the basis of immunization against toxic death of mice.基于对小鼠毒性致死免疫的沙眼菌株鉴别

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Isolation of trachoma virus from patients in West Africa.从西非患者中分离沙眼病毒。

J Hyg (Lond). 1960 Mar;58(1):99-108. doi: 10.1017/s0022172400038158.

4

Immunization of mice against toxic doses of homologous elementary bodies of trachoma.用沙眼同源原体的毒性剂量对小鼠进行免疫接种。

Science. 1959 Sep 11;130(3376):626-7. doi: 10.1126/science.130.3376.626.

5

Isolation of trachoma virus in embryonate eggs.在鸡胚中分离沙眼病毒。

Lancet. 1958 May 10;1(7028):993-6. doi: 10.1016/s0140-6736(58)91800-2.

6

Plaque formation and isolation of pure lines with poliomyelitis viruses.脊髓灰质炎病毒的噬斑形成及纯系分离

J Exp Med. 1954 Feb;99(2):167-82. doi: 10.1084/jem.99.2.167.

7

Further classification of TRIC agents from ocular trachoma and other sources by the mouse toxicity prevention test.通过小鼠毒性预防试验对来自眼沙眼和其他来源的TRIC制剂进行进一步分类。

Am J Ophthalmol. 1967 May;63(5):Suppl:1469-78. doi: 10.1016/0002-9394(67)94133-5.

8

The application of an in vitro typing test to TRIC Bedsoniae.

Am J Ophthalmol. 1967 May;63(5):Suppl:1429-37. doi: 10.1016/0002-9394(67)94127-x.

9

The use of graded density filters made by photography in fluorescence microscopy.

J Pathol Bacteriol. 1968 Jul;96(1):238-42. doi: 10.1002/path.1700960130.

10

The serum and conjunctival antibody response to trachoma in Gambian children.冈比亚儿童对沙眼的血清及结膜抗体反应。

J Hyg (Lond). 1972 Dec;70(4):727-40. doi: 10.1017/s0022172400022579.

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