Sheng Jason, Yu Brian Edward, Fong Maggie S Y, Hutnik Cindy, Malvankar-Mehta Monali S
Department of Epidemiology and Biostatistics, Western University, London, Canada.
Patient Relat Outcome Meas. 2025 Dec 1;16:181-190. doi: 10.2147/PROM.S535666. eCollection 2025.
The primary objective of this study is to assess the feasibility of administering an online meditation program compared to usual care to glaucoma patients to improve mental health outcomes such as quality of life, depression, anxiety, and sleep quality. The secondary objective of this study is to improve mental health outcomes among glaucoma patients.
This is a study protocol for a 12-week randomized control trial employing a mixed methods design. Glaucoma patients will be recruited from the Ivey Eye Institute in St. Joseph's Hospital Center. Eligible patients will include glaucoma patients of at least 75 years of age. Consented participants will be randomized to an online meditation group or usual care group in blocks of 4, or 2 per arm. Patients assigned to the online meditation group will undergo guided meditation sessions led by a meditation instructor via Microsoft Teams. Patients randomized to the usual care arm will undergo their usual glaucoma treatment. All study questionnaires including feasibility metrics, SF-12, CES-D, HADS-A and PSQI will be administered to both treatment groups at week 1, week 3, week 6, and week 12. Following study conclusion, feasibility metrics will be sent to participants in the intervention arm. In addition, patients randomized to the usual care arm will be given the opportunity to enroll in the meditation program after the 12 week study period, but no data will be collected.
To the best of the authors' knowledge, this study is the first of its kind to assess the feasibility of administering an online meditation intervention to glaucoma patients. If the findings from this study demonstrate positive results in favor of the treatment, this will be used to justify larger clinical trials and eventually, the integration of online meditation into the standard of care for glaucoma patients.
本研究的主要目的是评估与常规护理相比，为青光眼患者提供在线冥想项目以改善心理健康结果（如生活质量、抑郁、焦虑和睡眠质量）的可行性。本研究的次要目的是改善青光眼患者的心理健康结果。
这是一项采用混合方法设计的为期12周的随机对照试验的研究方案。青光眼患者将从圣约瑟夫医院中心的艾维眼科研究所招募。符合条件的患者将包括至少75岁的青光眼患者。同意参与的参与者将以4人为一组或每组2人随机分为在线冥想组或常规护理组。分配到在线冥想组的患者将通过微软团队参加由冥想导师指导的冥想课程。随机分配到常规护理组的患者将接受其常规的青光眼治疗。所有研究问卷，包括可行性指标、SF - 12、CES - D、HADS - A和PSQI，将在第1周、第3周、第6周和第12周分别施用于两个治疗组。研究结束后，可行性指标将发送给干预组的参与者。此外，随机分配到常规护理组的患者将在12周研究期后有机会参加冥想项目，但不收集数据。
据作者所知，本研究是同类研究中首个评估对青光眼患者进行在线冥想干预可行性的研究。如果本研究结果显示出有利于该治疗方法的积极结果，这将用于为更大规模的临床试验提供依据，并最终将在线冥想纳入青光眼患者的标准护理中。
