Pipy B, Béraud M, Gaillard D
Experientia. 1978 Jan 15;34(1):87-8. doi: 10.1007/BF01921919.
The effects of 4 carbaryl doses (0.375, 0.75, 1.50 and 3 mg/100 g) on the reticuloendothelial system (RES) phagocytic activity were studied 1 h after their administration to male rats. Carbaryl reduced RES phagocytic activity. Results showed a dose-dependent drop in RES phagocytic activity. Carbaryl might act as an inhibitor of phagocytes by saturing them to greater or lesser degree, depending on the dose administered.
研究了4种西维因剂量(0.375、0.75、1.50和3毫克/100克)对雄性大鼠给药1小时后网状内皮系统(RES)吞噬活性的影响。西维因降低了RES的吞噬活性。结果显示RES吞噬活性呈剂量依赖性下降。根据给药剂量不同,西维因可能通过不同程度地饱和吞噬细胞而起到吞噬细胞抑制剂的作用。