Temple A, Loewi G
Immunology. 1971 May;20(5):799-802.
Inbred August rats show strong delayed hypersensitivity following immunization with bovine γ-globulin or keyhole limpet haemocyanin in Freund's complete adjuvant as measured by increment of ear thickness at 24 hours. The reactions to PPD and keyhole limpet haemocyanin (but not bovine γ-globulin) are readily transferred by peritoneal exudate cells and to a lesser extent by lymph node cells. In contrast Blackhood rats give weaker active and passive delayed hypersensitivity reactions.
近交系八月龄大鼠在用弗氏完全佐剂中的牛γ球蛋白或钥孔戚血蓝蛋白免疫后,表现出强烈的迟发型超敏反应,这可通过24小时时耳厚度的增加来测量。对结核菌素纯蛋白衍生物(PPD)和钥孔戚血蓝蛋白(但不是牛γ球蛋白)的反应很容易被腹腔渗出细胞转移,淋巴结细胞转移的程度较小。相比之下,黑帽大鼠的主动和被动迟发型超敏反应较弱。