Hall P C, Ibbotson R M
J Clin Pathol. 1974 Jul;27(7):583-4. doi: 10.1136/jcp.27.7.583.
In five patients whose serum contained a paraprotein it has been shown that platelet counts obtained using the Technicon AutoCounter are much too high. In two patients with IgG gammopathy the error is caused by some factor in the red cells lysed by the diluent solution 2M urea. In three patients with IgM gammopathy spurious platelet counts were produced by platelet-poor plasma when diluted with 2M urea. It is recommended that at the present time no patient known to have a paraprotein should have platelet counts performed on the AutoCounter.
在五名血清中含有副蛋白的患者中，已表明使用Technicon自动计数器获得的血小板计数过高。在两名患有IgG丙种球蛋白病的患者中，误差是由2M尿素稀释液裂解红细胞中的某些因素引起的。在三名患有IgM丙种球蛋白病的患者中，用2M尿素稀释时，血小板缺乏的血浆产生了假性血小板计数。建议目前已知患有副蛋白的患者不要使用自动计数器进行血小板计数。
