Moss A A
AJR Am J Roentgenol. 1977 Jun;128(6):931-3. doi: 10.2214/ajr.128.6.931.
Biliary tract opacification was assessed in a double-blind clinical study that compared iodoxamate with iodipamide. Both drip infusion and direct (bolus) intravenous cholangiography were used to administer the contrast agents. The infusion method with either agent produced better opacification than bolus administration. Regardless of method used, iodoxamate produced greater biliary tract opacification, fewer unexplained failures, and fewer contrast reactions. Neither agent was successful in patients with elevated bilirubin levels, nor did either agent alter hepatic, renal, or hematologic function.
在一项双盲临床研究中对胆影脒和胆影葡胺进行了比较，评估了胆道显影情况。采用静脉滴注和直接（大剂量）静脉胆管造影两种方式给予造影剂。两种药物采用滴注法给药时的显影效果均优于大剂量给药法。无论采用哪种方式，胆影脒的胆道显影效果更好，原因不明的显影失败情况更少，造影剂不良反应也更少。对于胆红素水平升高的患者，两种药物均未成功显影，且两种药物均未改变肝脏、肾脏或血液学功能。
