普萘洛尔与Ro 3-3528治疗甲状腺功能亢进性心动过速和心律失常的比较。
Comparison of propranolol and Ro 3-3528 in hyperthyroid tachycardia and dysrhythmias.
作者信息
Phillips E M, Turner P, Houghton J, Ferriman D G
出版信息
Postgrad Med J. 1973 Jan;49(567):18-23. doi: 10.1136/pgmj.49.567.18.
Abstract
Ro 3-3528, a non-selective β-adrenoceptor blocking drug which lacks intrinsic activity, produces a dose-response effect in hyperthyroid tachycardia, and shows no dysrhythmic properties. In hyperthyroid patients, β-blocking drugs of this nature are preferable to those possessing intrinsic sympathomimetic activity, which may have dysrhythmic properties in this condition.
摘要
罗 3-3528 是一种缺乏内在活性的非选择性β肾上腺素能受体阻断药物，在甲状腺功能亢进性心动过速中产生剂量反应效应，且无致心律失常特性。在甲状腺功能亢进患者中，这类性质的β受体阻断药物比具有内在拟交感活性的药物更可取，后者在这种情况下可能有致心律失常特性。
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