The formation of "K-region" epoxides as hepatic microsomal metabolites of 7-methylbenz(a)anthracene and 7,12-dimethylbenz(a)anthracene and their 7-hydroxymethyl derivatives.
作者信息
Keysell G R, Booth J, Grover P L, Hewer A, Sims P
出版信息
Biochem Pharmacol. 1973 Nov 15;22(22):2853-67. doi: 10.1016/0006-2952(73)90152-4.
PMID:4148602
Abstract
摘要
相似文献
1
The formation of "K-region" epoxides as hepatic microsomal metabolites of 7-methylbenz(a)anthracene and 7,12-dimethylbenz(a)anthracene and their 7-hydroxymethyl derivatives.
Biochem Pharmacol. 1973 Nov 15;22(22):2853-67. doi: 10.1016/0006-2952(73)90152-4.
2
Studies on the metabolism of 7-methylbenz-[a]anthracene and 7,12-dimethylbenz[1]anthracene and its hydroxymethyl derivatives in rat liver and adrenal homogenates.7-甲基苯并[a]蒽和7,12-二甲基苯并[a]蒽及其羟甲基衍生物在大鼠肝脏和肾上腺匀浆中的代谢研究。
Biochem Pharmacol. 1970 Jul;19(7):2261-75. doi: 10.1016/0006-2952(70)90125-5.
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Epoxy derivatives of aromatic polycyclic hydrocarbons. The preparation and metabolism of epoxides related to 7,12-dimethylbenz(a)anthracene.芳香多环烃的环氧衍生物。与7,12-二甲基苯并(a)蒽相关的环氧化物的制备与代谢。
Biochem J. 1973 Feb;131(2):405-13. doi: 10.1042/bj1310405.
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Formation of epoxides as microsomal metabolites of polycyclic hydrocarbons.环氧化物作为多环烃微粒体代谢产物的形成。
Biochem J. 1971 Nov;125(2):28P. doi: 10.1042/bj1250028pa.
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The formation of an epoxide in the microsomal metabolism of 7,12-dimethylbenz(a)anthracene.7,12-二甲基苯并(a)蒽微粒体代谢过程中环氧物的形成。
Biochem J. 1972 Sep;129(3):41P-42P. doi: 10.1042/bj1290041pb.
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Formation of K-region epoxides as microsomal metabolites of pyrene and benzo(a)pyrene.芘和苯并(a)芘的微粒体代谢产物K-区域环氧化物的形成。
Biochem Pharmacol. 1972 Oct 15;21(20):2713-26. doi: 10.1016/0006-2952(72)90020-2.
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Metabolism of 7-hydroxymethyl-12-methylbenz(a)anthracene-12-14C in vitro.7-羟甲基-12-甲基苯并(a)蒽-12-¹⁴C的体外代谢
Biochem Pharmacol. 1969 Mar;18(3):680-2. doi: 10.1016/0006-2952(69)90094-x.
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Metabolic pathways of 7,12-dimethylbenz[a]anthracene in hepatic microsomes.7,12-二甲基苯并[a]蒽在肝微粒体中的代谢途径。
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2601-5. doi: 10.1073/pnas.72.7.2601.
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An epoxide is an intermediate in the microsomal metabolism of the chemical carcinogen, dibenz(a,h)anthracene.环氧化物是化学致癌物二苯并(a,h)蒽微粒体代谢过程中的一种中间体。
Biochem Biophys Res Commun. 1971 Jun 4;43(5):1010-6. doi: 10.1016/0006-291x(71)90562-6.
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Metabolism of benz(a)anthracene epoxides by rat-liver.
Biochem Pharmacol. 1974 Sep 15;23(18):2547-55. doi: 10.1016/0006-2952(74)90177-4.
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The carcinogenicity of polycyclic hydrocarbon epoxides in newborn mice.多环烃环氧化物对新生小鼠的致癌性。
Br J Cancer. 1975 Feb;31(2):182-8. doi: 10.1038/bjc.1975.24.
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Metabolic pathways of 7,12-dimethylbenz[a]anthracene in hepatic microsomes.7,12-二甲基苯并[a]蒽在肝微粒体中的代谢途径。
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2601-5. doi: 10.1073/pnas.72.7.2601.
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