Gisolfi C V, Mora F, Nattermann R, Myers R D
J Appl Physiol Respir Environ Exerc Physiol. 1978 Jan;44(1):129-32. doi: 10.1152/jappl.1978.44.1.129.
A new apparatus and method for exercising a monkey seated in a primate chair are described. The apparatus consists of a set of hand and foot bars mounted at either end of a rocker arm that pivots in a vertical plane. This arm is connected by a steel cable to a wooden box that houses lead weights. By simultaneously pushing the foot bar and pulling the hand bar, the monkey lifts a weight and triggers a microswitch which releases a banana-flavored food pellet into a well close to the animal's mouth. The amount of work performed is varied by changing the a) amount of weight to be lifted, b) distance the weight must be lifted, or c) number of times that the animal lifts the weight for a single reward. During 30 min of exercise, the heart rate of a given monkey rose 120 beats/min, respiratory rate 24/min, and colonic temperature 1.2 degrees C above base-line values. Total work performed in 30 min varied from 250 to 360 kpm. Major advantages of this apparatus over a treadmill or bicycle ergometer are that the animal 1) is restrained sufficiently to permit the delicate experimental manipulations and physiological measurements, 2) can be exercised strenuously in a quantitative fashion, and 3) is readily trained to perform the task in a short time.
描述了一种用于使坐在灵长类动物椅上的猴子进行锻炼的新装置和方法。该装置由一组安装在摇臂两端的手杆和脚杆组成,摇臂在垂直平面内枢转。该摇臂通过钢缆连接到一个装有铅锤的木箱。猴子通过同时推脚杆和拉手杆来提起重物并触发一个微动开关,该开关会将一颗香蕉味的食物颗粒释放到靠近动物嘴巴的一个孔中。通过改变以下因素来改变所做的功的量:a)要提起的重物的量,b)重物必须被提起的距离,或c)动物为获得一次奖励而提起重物的次数。在30分钟的锻炼过程中,某只猴子的心率上升了120次/分钟,呼吸频率上升了24次/分钟,结肠温度比基线值高出1.2摄氏度。30分钟内所做的总功在250至360千帕米之间变化。与跑步机或自行车测力计相比,该装置的主要优点是:1)动物受到足够的约束,以允许进行精细的实验操作和生理测量;2)可以以定量的方式进行剧烈锻炼;3)很容易在短时间内训练其执行任务。