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本地治里的先天性眼部异常

Congenital ocular anomalies in Pondicherry.

作者信息

Kapoor S, Kapoor M

出版信息

J Pediatr Ophthalmol. 1977 Nov-Dec;14(6):382-9.

PMID:415130
Abstract

Congenital anomalies of the eye and ocular adnexa occurring in Pondicherry have been described. Anophthalmos, microphthalmos, limbal dermoids, nervus of Ota, anterior lenticonus, buphthalmos, and congenital cataract are very common. Onset of cataract in young individuals was caused by abnormal aminoaciduria. Hereditary factors played a part in 59 percent of the cases who would have become blind if they were not treated. Consanguinity is a major factor in their pathogenesis. Avitaminosis A and systemic infections which are common here may be playing a significant role in their etiology.

摘要

已对本地治里地区发生的眼及眼附属器先天性异常进行了描述。无眼、小眼、角膜皮样瘤、太田痣、前圆锥形晶状体、牛眼以及先天性白内障都很常见。年轻个体白内障的发病是由异常氨基酸尿症引起的。在59%的病例中,遗传因素起了作用,若不治疗,这些病例将会失明。近亲结婚是其发病机制中的一个主要因素。维生素A缺乏症和本地常见的全身性感染可能在其病因学中发挥重要作用。

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