Inhibition of coenzyme Q10-enzymes, succinoxidase and NADH-oxidase, by adriamycin and other quinones having antitumor activity.

Suppr

超能文献

作者信息

Iwamoto Y, Hansen I L, Porter T H, Folkers K

出版信息

Biochem Biophys Res Commun. 1974 Jun 4;58(3):633-8. doi: 10.1016/s0006-291x(74)80465-1.

DOI:10.1016/s0006-291x(74)80465-1

PMID:4152017

Abstract

摘要

相似文献

Inhibition of coenzyme Q10-enzymes, succinoxidase and NADH-oxidase, by adriamycin and other quinones having antitumor activity.

Biochem Biophys Res Commun. 1974 Jun 4;58(3):633-8. doi: 10.1016/s0006-291x(74)80465-1.

Bioenergetics in clinical medicine: prevention by forms of coenzyme Q of the inhibition by adriamycin of coenzyme Q10-enzymes in mitochondria of the myocardium.临床医学中的生物能量学：辅酶Q的形式对阿霉素抑制心肌线粒体中辅酶Q10-酶的预防作用。

Proc Natl Acad Sci U S A. 1976 Dec;73(12):4653-6. doi: 10.1073/pnas.73.12.4653.

Antimetabolites of coenzyme Q. 14. Quinolinequinone analogs which inhibit mitochondrial DPNH-oxidase and succinoxidase.辅酶Q的抗代谢物。14. 抑制线粒体DPNH氧化酶和琥珀酸氧化酶的喹啉醌类似物。

J Med Chem. 1973 Mar;16(3):206-9. doi: 10.1021/jm00261a008.

Potential bioreductive alkylating agents. 4. Inhibition of coenzyme Q enzyme systems by lipoidal benzoquinone and naphthoquinone derivatives.潜在的生物还原烷基化剂。4. 类脂苯醌和萘醌衍生物对辅酶Q酶系统的抑制作用。

J Med Chem. 1974 Jul;17(7):688-7.

Bioenergetics in clinical medicine. III. Inhibition of coenzyme Q10-enzymes by clinically used anti-hypertensive drugs.

Res Commun Chem Pathol Pharmacol. 1975 Nov;12(3):533-40.

Mutual inhibition between NADH oxidase and succinoxidase activities in respiring submitochondrial particles.

FEBS Lett. 1972 Oct 1;26(1):207-10. doi: 10.1016/0014-5793(72)80574-x.

New alkylmercapto-2,3-dimethoxy-1,4-benzoquinones as inhibitors of coenzyme Q systems.新型烷基巯基-2,3-二甲氧基-1,4-苯醌作为辅酶Q系统的抑制剂

Acta Pharm Suec. 1977;14(2):171-80.

Synthesis and inhibitory activity of new ethylenedioxyquinones as analogs of coenzyme Q.新型乙二氧基醌作为辅酶Q类似物的合成及抑制活性

J Med Chem. 1973 Sep;16(9):988-91. doi: 10.1021/jm00267a007.

Inhibitory effects of several anthracyclines on mitochondrial respiration and coenzyme Q10 protection.几种蒽环类药物对线粒体呼吸的抑制作用及辅酶Q10的保护作用。

Drugs Exp Clin Res. 1985;11(8):533-7.

Synthesis and bioassays of a new dimethoxyalkylmercapto-1,4-benzoquinones.一种新型二甲氧基烷基巯基-1,4-苯醌的合成与生物测定

J Med Chem. 1974 Aug;17(8):893-6. doi: 10.1021/jm00254a023.

引用本文的文献

Cardiotoxic effects of anthracyclines.蒽环类药物的心脏毒性作用。

West J Med. 1983 Sep;139(3):369-71.

Detection of adriamycin-induced cardiotoxicity in cultured heart cells with technetium 99m-SESTAMIBI.用锝99m-甲氧基异丁基异腈检测阿霉素诱导的培养心肌细胞的心脏毒性。

Cancer Chemother Pharmacol. 1993;32(5):385-91. doi: 10.1007/BF00735924.

Adriamycin and daunomycin dose-dependent effects upon contractions of isolated rat myocytes.阿霉素和柔红霉素对离体大鼠心肌细胞收缩的剂量依赖性效应。

Cancer Chemother Pharmacol. 1980;5(1):61-5. doi: 10.1007/BF00578564.

The British Association for Cancer Research, 23rd annual general meeting. Edinburgh 29--31 March 1982. Abstracts.英国癌症研究协会，第23届年会。1982年3月29日至31日，爱丁堡。摘要。

Br J Cancer. 1982 Sep;46(3):459-516. doi: 10.1038/bjc.1982.227.

Covalent protein binding of reactive adriamycin metabolites in rat liver and rat heart microsomes.阿霉素活性代谢产物在大鼠肝脏和大鼠心脏微粒体中的共价蛋白结合。

J Cancer Res Clin Oncol. 1982;103(1):39-48. doi: 10.1007/BF00410304.

Resistance to adriamycin cytotoxicity among respiratory-deficient mutants in yeast.酵母呼吸缺陷型突变体对阿霉素细胞毒性的抗性。

Antimicrob Agents Chemother. 1980 Mar;17(3):443-9. doi: 10.1128/AAC.17.3.443.

Anthracycline cardiomyopathy.蒽环类药物性心肌病

Pediatr Cardiol. 1982;3(3):265-72. doi: 10.1007/BF02240463.

The mechanism of action of quinone antibiotics.醌类抗生素的作用机制。

Mol Cell Biochem. 1983;55(1):17-40. doi: 10.1007/BF00229240.

The regulation of protein synthesis in heart muscle under normal conditions and in the adriamycin-cardiomyopathy.正常条件下以及阿霉素诱导的心肌病状态下心肌中蛋白质合成的调控

Klin Wochenschr. 1981 Dec 1;59(23):1273-87. doi: 10.1007/BF01711177.

Acute effect of calcium channel blockers on adriamycin exposed isolated adult cardiocytes.钙通道阻滞剂对阿霉素处理的离体成年心肌细胞的急性作用。

Basic Res Cardiol. 1985 Nov-Dec;80(6):626-35. doi: 10.1007/BF01907861.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验