• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Lymphocyte deactivation by (potential immunosuppressant) alkylating metabolites of cyclophosphamide.

作者信息

Whitehouse M W, Beck F W, Dröge M M, Struck R F

出版信息

Agents Actions. 1974 Apr;4(2):117-24. doi: 10.1007/BF01966821.

DOI:10.1007/BF01966821
PMID:4152287
Abstract
摘要

相似文献

1
Lymphocyte deactivation by (potential immunosuppressant) alkylating metabolites of cyclophosphamide.
Agents Actions. 1974 Apr;4(2):117-24. doi: 10.1007/BF01966821.
2
Effect of cyclophosphamide on a local graft-versus-host reaction in the rat: influence of sex, disease and different dosage regimens.环磷酰胺对大鼠局部移植物抗宿主反应的影响：性别、疾病及不同给药方案的作用
Agents Actions. 1973 Jun;3(2):53-60. doi: 10.1007/BF02023854.
3
Studies on the mechanism of denaturation of cytochrome P-450 by cyclophosphamide and its metabolites.环磷酰胺及其代谢产物对细胞色素P - 450变性机制的研究。
J Biol Chem. 1981 Nov 25;256(22):11691-701.
4
Graft versus host reaction in the rat: effect of cyclosporin A and cyclophosphamide on lymphocyte subsets involved in GvHR.
Adv Exp Med Biol. 1985;186:539-44. doi: 10.1007/978-1-4613-2463-8_66.
5
Studies on immunosuppression by purine nucleoside analogues. II. Effects on skin-graft rejection and immediate hypersensitivity in mice.嘌呤核苷类似物的免疫抑制作用研究。II. 对小鼠皮肤移植排斥和速发型超敏反应的影响。
Biochem Pharmacol. 1969 Sep;18(9):2123-34. doi: 10.1016/0006-2952(69)90317-7.
6
[Immunosuppressant effect of cyclophosphamide activated in vitro by liver microsomes from different strains of mice].[不同品系小鼠肝脏微粒体体外激活环磷酰胺的免疫抑制作用]
Biull Eksp Biol Med. 1981 Jul;92(7):57-60.
7
Effect of intrasplenic injection of parental splenocytes on systemic graft-versus-host reaction in adult F1 mice pretreated with cyclophosphamide.脾脏内注射亲代脾细胞对经环磷酰胺预处理的成年F1小鼠全身移植物抗宿主反应的影响。
Folia Biol (Krakow). 1985;33(1-2):73-82.
8
A contribution to the mechanism of drug inhibition of the graft vs host reaction.药物抑制移植物抗宿主反应机制的一项研究
J Reticuloendothel Soc. 1973 Jan;13(1):1-6.
9
Effect of N-acetylcysteine on some aspects of cyclophosphamide-induced toxicity and immunosuppression.N-乙酰半胱氨酸对环磷酰胺诱导的毒性和免疫抑制某些方面的影响。
Biochem Pharmacol. 1977 Jun 1;26(11):1015-20. doi: 10.1016/0006-2952(77)90237-4.
10
[Effect of temporary cyclophosphamide treatment upon allogenic rat parabioses].[环磷酰胺短期治疗对同种异体大鼠联体生活的影响]
Z Gesamte Exp Med Einschl Exp Chir. 1969 Dec 31;151(4):321-30.

引用本文的文献

1
Irritancy of cyclophosphamide-derived aldehydes (acrolein, chloracetaldehyde) and their effect on lymphocyte distribution in vivo: protective effect of thiols and bisulphite ions1).
Agents Actions. 1975 Dec;5(5):541-8. doi: 10.1007/BF01972692.
2
Timely appraisal: ectopic (exocellular) nucleic acid as a drug target, especially in rheumatoid arthritis and certain cancers(?).
Agents Actions. 1975 Dec;5(5):508-11. doi: 10.1007/BF01972687.

本文引用的文献

1
Formation of the cytotoxic aldehyde acrolein during in vitro degradation of cyclophosphamide.环磷酰胺体外降解过程中细胞毒性醛丙烯醛的形成。
Nat New Biol. 1971 Oct 20;233(42):250-2. doi: 10.1038/newbio233250b0.
2
[BIS-(BETA-CHLOROETHYL)-AMINE AND N-BETA-CHLOROETHYLAZIRIDINE AS RESULTING PRODUCTS OF BIOLOGICAL "ACTIVATION" OF CYCLOPHOSPHAMIDE].[双（β-氯乙基）胺和N-β-氯乙基氮丙啶作为环磷酰胺生物“活化”的产物]
Arzneimittelforschung. 1964 Feb;14:159.
3
[SYNTHESIS OF N,N-BIS-(2-CHLOROETHYL)-0-(3-AMINOPROPYL)-PHOSPHORIC ACID AMIDE ESTER].
N,N-双（2-氯乙基）-O-（3-氨基丙基）磷酸酰胺酯的合成
Arzneimittelforschung. 1963 Oct;13:927-8.
4
Ascorbic acid in aromatic hydroxylation. I. A model system for aromatic hydroxylation.抗坏血酸在芳香族羟基化反应中的作用。I. 芳香族羟基化反应的模型体系。
J Biol Chem. 1954 Jun;208(2):731-9.
5
Cyclophosphamide inhibition of experimental allergic encephalomyelitis in Wistar rats.
Proc Soc Exp Biol Med. 1967 Mar;124(3):928-32. doi: 10.3181/00379727-124-31888.
6
Cyclophosphamide: effect on experimental allergic encephalomyelitis in Lewis rats.
Science. 1969 Jul 11;165(3889):191-2. doi: 10.1126/science.165.3889.191.
7
Isolation and identification of 4-ketocyclophosphamide, a possible active form of the antitumor agent cyclophosphamide.抗肿瘤药物环磷酰胺的一种可能活性形式——4-酮环磷酰胺的分离与鉴定。
J Am Chem Soc. 1970 May 20;92(10):3207-8. doi: 10.1021/ja00713a060.
8
Prophylactic effects of cyclophosphamide in adjuvant-induced arthritis.环磷酰胺在佐剂性关节炎中的预防作用。
Arch Int Pharmacodyn Ther. 1970 Jan;183(1):1-11.
9
Chemotherapy of experimental allergic encephalomyelitis (EAE).实验性变应性脑脊髓炎（EAE）的化学疗法
Arch Int Pharmacodyn Ther. 1969 Jun;179(2):251-75.
10
Urinary metabolites of the antitumor agent cyclophosphamide.抗肿瘤药物环磷酰胺的尿液代谢产物。
Mol Pharmacol. 1971 Sep;7(5):519-29.