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Urinary metabolites of the antitumor agent cyclophosphamide.

作者信息

Struck R F, Kirk M C, Mellett L B, el Dareer S, Hill D L

出版信息

Mol Pharmacol. 1971 Sep;7(5):519-29.

PMID:5139563
Abstract
摘要

相似文献

1
Urinary metabolites of the antitumor agent cyclophosphamide.抗肿瘤药物环磷酰胺的尿液代谢产物。
Mol Pharmacol. 1971 Sep;7(5):519-29.
2
Metabolism of iphosphamide (2-(2-chloroethylamino)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide) and production of a toxic iphosphamide metabolite.
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Antitumor activity of monomeric and polymeric cyclophosphamide derivatives compared with in vitro hydrolysis.
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Chemical stability and fate of the cytostatic drug ifosfamide and its N-dechloroethylated metabolites in acidic aqueous solutions.细胞抑制药物异环磷酰胺及其N-去氯乙基代谢物在酸性水溶液中的化学稳定性和归宿
J Med Chem. 1999 Jul 15;42(14):2542-60. doi: 10.1021/jm980587g.
6
Transport and accumulation of triazenoimidazoles by L1210 cells.L1210细胞对三氮烯咪唑的转运与积累
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[Chemistry of sphingoglycolipids (I) (author's transl)].鞘糖脂的化学（I）（作者译）
Tanpakushitsu Kakusan Koso. 1974 Jul;19(7):499-513.
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Synthesis, cytotoxicity and antitumor activity of platinum(II) complexes of cyclopentanecarboxylic acid hydrazide.环戊烷羧酸酰肼铂（II）配合物的合成、细胞毒性及抗肿瘤活性
Biol Chem. 1999 Nov;380(11):1287-94. doi: 10.1515/BC.1999.164.
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Disposition of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide, a new antitumor agent.新型抗肿瘤药物5-（3,3-二甲基-1-三氮烯基）咪唑-4-甲酰胺的处置
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Studies of resistance to methylglyoxal-bis-guanylhydrazone and its metabolic fate in tumor-bearing rodents.荷瘤啮齿动物对丙脒腙的抗性及其代谢命运的研究。
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引用本文的文献

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Insights into Mechanisms of Electrochemical Drug Degradation in Their Mixtures in the Split-Flow Reactor.在分流反应器中电化学药物降解混合物的机制研究。
Molecules. 2019 Nov 28;24(23):4356. doi: 10.3390/molecules24234356.
2
Proton magnetic resonance studies of the decomposition of 4-hydroxycyclophosphamide, a microsomal metabolite of cyclophosphamide.质子磁共振研究 4-羟基环磷酰胺的分解，环磷酰胺的一种微粒体代谢物。
Pharm Res. 1984 Mar;1(2):89-92. doi: 10.1023/A:1016307515811.
3
Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC-ESI-QTOFMS-based metabolomics.
基于 UPLC-ESI-QTOFMS 的代谢组学研究在小鼠体内环磷酰胺和异环磷酰胺的比较代谢。
Biochem Pharmacol. 2010 Oct 1;80(7):1063-74. doi: 10.1016/j.bcp.2010.06.002. Epub 2010 Jun 10.
4
Carbon tetrachloride-induced increase in the antitumor activity of cyclophosphamide in mice: a pharmacokinetic study.
Cancer Chemother Pharmacol. 1984;12(3):167-72. doi: 10.1007/BF00256539.
5
Enzymatic toxicogenation of "activated" cyclophosphamide by 3'-5' exonucleases.3'-5'核酸外切酶对“活化”环磷酰胺的酶促毒化作用。
J Cancer Res Clin Oncol. 1983;105(1):27-9. doi: 10.1007/BF00391828.
6
Clinical pharmacokinetics of commonly used anticancer drugs.常用抗癌药物的临床药代动力学
Clin Pharmacokinet. 1983 May-Jun;8(3):202-32. doi: 10.2165/00003088-198308030-00002.
7
In vitro microassay for biological activity of cyclophosphamide metabolites.环磷酰胺代谢物生物活性的体外微量测定
Antimicrob Agents Chemother. 1973 Mar;3(3):407-11. doi: 10.1128/AAC.3.3.407.
8
Formation of 4-ketocyclophosphamide by the oxidation of cyclophosphamide with KMnO4.用高锰酸钾氧化环磷酰胺生成4-酮环磷酰胺。
Experientia. 1973;29(7):812-4. doi: 10.1007/BF01946302.
9
The effect of microsomal enzyme inhibition on the immunosuppressive and toxic effects of cyclophosphamide.微粒体酶抑制对环磷酰胺免疫抑制及毒性作用的影响。
Clin Exp Immunol. 1973 Jun;14(2):257-70.
10
[Metabolic pathways of cyclophosphamide].
Klin Wochenschr. 1972 May 1;50(9):449-53. doi: 10.1007/BF01487599.