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地西泮对大鼠食物摄入量的影响。

Effect of diazepam on food consumption in rats.

作者信息

Johnson D N

出版信息

Psychopharmacology (Berl). 1978 Jan 31;56(1):111-2. doi: 10.1007/BF00571417.

Abstract

Diazepam significantly increased milk consumption in rats that had never been exposed to this food before but not in rats trained to drink milk. Diazepam failed to increase lever-pressing for food reward except when this behavior had been previously suppressed by the simultaneous administration of electric shock. These data suggest that diazepam does not alter appetite, but enhances the expression of motivation suppressed by instinct or training.

摘要

地西泮显著增加了此前从未接触过这种食物的大鼠的牛奶摄入量,但对经过训练饮用牛奶的大鼠则没有这种作用。地西泮未能增加为获取食物奖励而按压杠杆的行为,除非此前这种行为因同时施加电击而受到抑制。这些数据表明,地西泮不会改变食欲,但会增强因本能或训练而受到抑制的动机表达。

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