γ-氨基丁酸对垂体促性腺激素分泌的影响。
Gamma-aminobutyric acid effects on pituitary gonadotropin secretion.
作者信息
Ondo J G
出版信息
Science. 1974 Nov 22;186(4165):738-9. doi: 10.1126/science.186.4165.738.
PMID:4153578
Abstract
Gamma-aminobutyric acid (GABA) injected into the third ventricle of male rats promotes the release of pituitary luteinizing hormone (LH) but not follicle-stimulating hormone. When GABA was injected directly into the pituitary it was ineffective in promoting LH release. This evidence suggests that GABA may play a role in controlling the discharge of hypothalamic luteinizing hormone releasing factor.
摘要
向雄性大鼠的第三脑室注射γ-氨基丁酸（GABA）可促进垂体促黄体生成素（LH）的释放，但对促卵泡激素无效。当将GABA直接注射到垂体时，它对促进LH释放无效。这一证据表明，GABA可能在控制下丘脑促黄体生成素释放因子的释放中起作用。
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