Mayer M L
Exp Brain Res. 1981;43(2):154-8. doi: 10.1007/BF00237759.
Extracellular recordings were made from preoptic-anterior hypothalamic neurones with combined recording and iontophoresis electrodes. Short iontophoretic applications of beta-alanine, GABA, glycine and taurine inhibited the discharge of the majority of neurones tested. Bicuculline metho-chloride reversibly and selectively antagonised GABA responses. Strychnine reversibly antagonised beta-alanine, glycine and taurine but not GABA responses. These results suggest the existence of two populations of inhibitory amino acid receptors in the preoptic-anterior hypothalamus. The function of inhibitory amino acids in the rostral hypothalamus was briefly discussed.
使用联合记录和离子电泳电极，对视前区-下丘脑前部神经元进行细胞外记录。短暂离子电泳施加β-丙氨酸、γ-氨基丁酸（GABA）、甘氨酸和牛磺酸可抑制大多数被测试神经元的放电。氯化甲基荷包牡丹碱可逆且选择性地拮抗GABA反应。士的宁可逆地拮抗β-丙氨酸、甘氨酸和牛磺酸，但不拮抗GABA反应。这些结果表明，视前区-下丘脑前部存在两类抑制性氨基酸受体。文中简要讨论了抑制性氨基酸在 Rostral 下丘脑的功能。
