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吲哚拉明对运动诱发哮喘的预防作用。

Prevention of exercise-induced asthma by indoramin.

作者信息

Bianco S, Griffin J P, Kamburoff P L, Prime F J

出版信息

Br Med J. 1974 Oct 5;4(5935):18-20. doi: 10.1136/bmj.4.5935.18.

Abstract

Indoramin, an alpha-adrenoceptor blocking drug, has been found to prevent the occurrence of exercise-induced bronchoconstriction. Evidence is provided in two cases that this was not due to the antihistamine properties of indoramin.

摘要

吲哚拉明是一种α-肾上腺素能受体阻断药,已发现它能预防运动诱发的支气管收缩。两个病例提供的证据表明,这并非归因于吲哚拉明的抗组胺特性。

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本文引用的文献

1
Changes in plasma concentration of epinephrine and norepinephrine with muscular work.
Proc Soc Exp Biol Med. 1957 Dec;96(3):636-8. doi: 10.3181/00379727-96-23561.
2
Pharmacologic studies of indoramin in man.
Clin Pharmacol Ther. 1972 May-Jun;13(3):380-92. doi: 10.1002/cpt1972133380.
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Competitive blockade of adrenergic alpha-receptors and histamine receptors by thymoxamine.
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Clinical evaluation of indoramin, a new antihypertensive agent.
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