Nuclear magnetic resonance studies of the binding of substrate analogs and coenzyme to dihydrofolate reductase from Lactobacillus casei.

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作者信息

Roberts G C, Feeney J, Burgen A S, Yuferov V, Dann J G, Bjur R

出版信息

Biochemistry. 1974 Dec 17;13(26):5351-7. doi: 10.1021/bi00723a015.

DOI:10.1021/bi00723a015

PMID:4154775

Abstract

摘要

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Nuclear magnetic resonance studies of the binding of substrate analogs and coenzyme to dihydrofolate reductase from Lactobacillus casei.

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1H nuclear magnetic resonance studies of the tyrosine residues of selectively deuterated Lactobacillus casei dihydrofolate reductase.选择性氘代干酪乳杆菌二氢叶酸还原酶酪氨酸残基的¹H核磁共振研究

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Proceedings: NMR studies of the binding of substrate analogues to L. casei dihydrofolate reductase.论文集：核磁共振研究底物类似物与干酪乳杆菌二氢叶酸还原酶的结合

Br J Pharmacol. 1974 May;51(1):126P-127P.

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A 1H n.m.r. study of the role of the glutamate moiety in the binding of methotrexate to Lactobacillus casei dihydrofolate reductase.一项关于谷氨酸部分在甲氨蝶呤与干酪乳杆菌二氢叶酸还原酶结合中作用的核磁共振氢谱研究。

Br J Pharmacol. 1984 Feb;81(2):309-15. doi: 10.1111/j.1476-5381.1984.tb10080.x.

Interactions between inhibitors of dihydrofolate reductase.二氢叶酸还原酶抑制剂之间的相互作用。

Biochem J. 1989 Mar 1;258(2):335-42. doi: 10.1042/bj2580335.

Interaction of methotrexate, folates, and pyridine nucleotides with dihydrofolate reductase: calorimetric and spectroscopic binding studies.甲氨蝶呤、叶酸和吡啶核苷酸与二氢叶酸还原酶的相互作用：量热法和光谱结合研究。

Proc Natl Acad Sci U S A. 1978 Jul;75(7):3201-5. doi: 10.1073/pnas.75.7.3201.

Large-scale purification and characterization of dihydrofolate reductase from a methotrexate-resistant strain of Lactobacillus casei.来自耐甲氨蝶呤干酪乳杆菌菌株的二氢叶酸还原酶的大规模纯化及特性鉴定

Biochem J. 1976 Sep 1;157(3):559-71. doi: 10.1042/bj1570559.

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