烟酰胺腺嘌呤二核苷酸还原反应的焓变。
The enthalpy change for the reduction of nicotinamide--adenine dinucleotide.
作者信息
Burton K
出版信息
Biochem J. 1974 Nov;143(2):365-8. doi: 10.1042/bj1430365.
Abstract
The heat of the reaction NAD(+)+propan-2-ol=NADH+acetone+H(+) was determined to be 42.5+/-0.6kJ/mol (10.17+/-0.15kcal/mol) from equilibrium measurements at 9-42 degrees C catalysed by yeast alcohol dehydrogenase. With the aid of thermochemical data for acetone and propan-2-ol the values of DeltaH=-29.2kJ/mol (-6.99kcal/mol) and DeltaG(0)=22.1kJ/mol (5.28kcal/mol) are derived for the reduction of NAD (NAD(+)+H(2)=NADH+H(+)). These values are consistent with analogous but less accurate data for the ethanol-acetaldehyde reaction. Thermodynamic data for the reduction of NAD and NADP are summarized.
摘要
通过在9至42摄氏度下由酵母醇脱氢酶催化的平衡测量，确定反应NAD(+)+丙醇-2=NADH+丙酮+H(+)的热为42.5±0.6kJ/mol(10.17±0.15kcal/mol)。借助丙酮和丙醇-2的热化学数据，得出还原NAD(NAD(+)+H₂=NADH+H(+))的ΔH=-29.2kJ/mol(-6.99kcal/mol)和ΔG(0)=22.1kJ/mol(5.28kcal/mol)的值。这些值与乙醇-乙醛反应的类似但不太准确的数据一致。总结了还原NAD和NADP的热力学数据。
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