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与母体摄入溶酶体贮积症相关的多种眼部异常。

Multiple ocular anomalies associated with maternal LSD ingestion.

作者信息

Chan C C, Fishman M, Egbert P R

出版信息

Arch Ophthalmol. 1978 Feb;96(2):282-4. doi: 10.1001/archopht.1978.03910050150009.

Abstract

Severe ocular malformations, including microphthalmos, intraocular cartilage, cataract, persistent hyperplastic primary vitreous, and retinal dysplasia, occurred in a premature baby girl. The mother had ingested LSD during the first trimester of pregnancy. To our knowledge, this is the third case reported of ocular teratogenesis associated with maternal LSD ingestion. Further cases must be documented to establish an actual cause and effect relationship between the drug and the induced malformations.

摘要

一名早产女婴出现了严重的眼部畸形,包括小眼球、眼内软骨、白内障、永存原始玻璃体增生症和视网膜发育异常。母亲在怀孕的头三个月摄入了麦角酸二乙胺(LSD)。据我们所知,这是第三例报道的与母亲摄入LSD相关的眼部致畸病例。必须记录更多病例,以确定药物与诱发畸形之间的实际因果关系。

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