过敏试验在抗原混合物研究中的适用性。I. 试验的敏感性。
The applicability of anaphylactic tests in studies of antigen mixtures. I. The sensitivity of the tests.
作者信息
Dale M M
出版信息
Immunology. 1965 May;8(5):435-43.
Abstract
The sensitivity of two anaphylactic tests, the Dale—Schultz reaction and the measurement of histamine released from chopped lung, have been investigated and compared in model systems. Both tests proved to be highly sensitive in animals sensitized to a single antigen, the Dale—Schultz test being more sensitive on occasion, but less consistent than histamine-release from the lung. In general, the sensitivity to a particular antigen was decreased if more than one antigen was used for sensitization.
摘要
在模型系统中，对两种过敏试验——戴尔-舒尔茨反应和切碎肺组织中组胺释放量的测定——的敏感性进行了研究和比较。结果证明，这两种试验在对单一抗原致敏的动物中都具有高度敏感性，戴尔-舒尔茨试验有时更为敏感，但不如肺组织组胺释放试验稳定。一般来说，如果使用多种抗原进行致敏，对特定抗原的敏感性会降低。
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