Lagrange P H
Dev Biol Stand. 1977;38:223-9.
Three tests have been selected to demonstrate the close relationship between the innate immunogenicity and immunopotentiating capacity of different strains of BCG vaccines grown under the same conditions. The five strains of BCG which have been most extensively studied were PASTEUR, PHIPPS, TICE, CONNAUGHT and GLAXO. The first four are alike, they have similar growth characteristics and closely resemble each other, in immunological properties-lymphoproliferative response in vivo and T-cell potentiating effect-PASTEUR BCG being the strongest. GLAXO strain is different in these respects and is shown to have atypical properties.
已选择三项试验来证明在相同条件下培养的不同卡介苗菌株的固有免疫原性和免疫增强能力之间的密切关系。研究最为广泛的五株卡介苗分别是巴斯德株、菲普斯株、蒂塞株、康诺特株和葛兰素株。前四株相似，它们具有相似的生长特性，在免疫特性方面彼此非常相似——体内淋巴细胞增殖反应和T细胞增强作用，其中巴斯德卡介苗最强。葛兰素株在这些方面有所不同，表现出非典型特性。
