抗免疫球蛋白A血清：组织培养中对细胞介导的脱髓鞘作用的抑制
Antiserum to immunoglobulin A: Inhibition of cell-mediated demyelination in tissue culture.
作者信息
Winkler G F, Arnason B G
出版信息
Science. 1966 Jul 1;153(3731):75-6. doi: 10.1126/science.153.3731.75.
PMID:4160943
Abstract
Lymph node cells from rats immunized with sciatic nerve in Freund's adjuvant demyelinate trigeminal ganglion cultures. Rabbit antiserum to rat immunoglobulin A blocks this cytodestructive event. The antiserum may act by combining with IgA on the lymphoid cell surface, preventing the interaction of cell-bound antibody and tissue anitigen.
摘要
用弗氏佐剂中的坐骨神经免疫的大鼠的淋巴结细胞可使三叉神经节培养物脱髓鞘。兔抗大鼠免疫球蛋白A抗血清可阻断这一细胞破坏过程。该抗血清可能通过与淋巴细胞表面的IgA结合起作用，从而阻止细胞结合抗体与组织抗原的相互作用。
Zotero 插件