大鼠胰岛同种异体移植增强作用的研究。
Studies on the enhancement of rat islet allografts.
作者信息
Nash J R, Peters M, Bell P R
出版信息
Transplantation. 1978 Apr;25(4):180-1. doi: 10.1097/00007890-197804000-00004.
Attempts to improve the induction of immunological enhancement of (AS X August)F1 pancreatic islet allografts in diabetic AS rats have been carried out. First, by treating the diabetic AS recipient with enhancing serum obtained from AS rats with functioning enhanced (AS X August)F1 islet allografts. In these rats on 1 of 5 islet allografts had a prolonged survival, the other 4 being rejected by 2 days. Second, by transplanting (AS X August)F1 islet allografts into diabetic AS rats bearing functioning enhanced (AS X August)F1 cardiac allografts. All of these islet allografts were rejected by 2 days.
已尝试改善在糖尿病AS大鼠中诱导（AS×奥古斯特）F1胰岛同种异体移植免疫增强的情况。首先，用从具有功能增强的（AS×奥古斯特）F1胰岛同种异体移植的AS大鼠获得的增强血清治疗糖尿病AS受体。在这些大鼠中，5个胰岛同种异体移植中有1个存活时间延长，其他4个在2天内被排斥。其次，将（AS×奥古斯特）F1胰岛同种异体移植到具有功能增强的（AS×奥古斯特）F1心脏同种异体移植的糖尿病AS大鼠中。所有这些胰岛同种异体移植在2天内被排斥。
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