Nielsen K, Nansen P
Can J Comp Med Vet Sci. 1967 Apr;31(4):106-10.
The turnover of I(131)-labelled IgG has been studied in cattle with mild hypoimmunoglobulinemia secondary to gastrointestinal disorders. A gastrointestinal loss of immunoglobulin was the most likely cause of the hypoimmunoglobulinemic condition. Thus, 6 animals with severe digestive symptoms (diarrhoea) had increased turnover rates of I(131)-IgG, whereas animals that had recovered from diarrhoeal diseases had normal or even low turnover rates (table I). It is concluded that the pattern of immunoglobulin metabolism is closely related to the clinical picture of the digestive disease.
对患有继发于胃肠道疾病的轻度低免疫球蛋白血症的牛，研究了碘（131）标记的免疫球蛋白G（IgG）的周转率。免疫球蛋白的胃肠道丢失是低免疫球蛋白血症最可能的原因。因此，6只患有严重消化症状（腹泻）的动物，其碘（131）-IgG的周转率增加，而从腹泻疾病中恢复的动物，其周转率正常甚至较低（表I）。得出的结论是，免疫球蛋白代谢模式与消化系统疾病的临床表现密切相关。
