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蛋白质-热量营养不良时红细胞膜的变化。

Changes in the red blood cell membrane in protein-calorie malnutrition.

作者信息

Brown K H, Suskind R M, Lubin B, Kulapongs P, Leitzmann C, Olson R E

出版信息

Am J Clin Nutr. 1978 Apr;31(4):574-8. doi: 10.1093/ajcn/31.4.574.

DOI:10.1093/ajcn/31.4.574
PMID:416706
Abstract

Ten children with protein-calorie malnutrition (five with kwashiorkor, three with marasmus, and two with marasmic-kwashiorkor) were studied at hospital admission and during recovery for evidence of changes in red blood cell lipids, osmotic fragility, and chromium survival. On admission, the children had significantly higher-than-normal red blood cell membrane cholesterol and phospholipid, and an elevated cholesterol:phospholipid ratio. Both red blood cell osmotic fragility and red cell survivals were depressed. These measurements returned to normal limits with recovery.

摘要

对10名蛋白质-热量营养不良的儿童(5名夸希奥科病患儿、3名消瘦症患儿和2名消瘦-夸希奥科病患儿)在入院时和康复期间进行了研究,以寻找红细胞脂质、渗透脆性和铬存活情况变化的证据。入院时,这些儿童的红细胞膜胆固醇和磷脂显著高于正常水平,胆固醇与磷脂的比例升高。红细胞渗透脆性和红细胞存活率均降低。随着康复,这些测量值恢复到正常范围。

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Changes in the red blood cell membrane in protein-calorie malnutrition.蛋白质-热量营养不良时红细胞膜的变化。
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Erythrocyte osmotic fragility in protein-energy malnutrition: cholesterol, phospholipid, and CA2+, Mg2+ adenosine triphosphatase.蛋白质-能量营养不良时的红细胞渗透脆性:胆固醇、磷脂以及Ca2+、Mg2+三磷酸腺苷酶
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引用本文的文献

1
Fatty acid composition of plasma lipids in Nigerian children with protein-energy malnutrition.患有蛋白质-能量营养不良的尼日利亚儿童血浆脂质的脂肪酸组成
Eur J Pediatr. 1986 Apr;145(1-2):109-15. doi: 10.1007/BF00441868.
2
The effect of dietary zinc deficiency on the lipid composition of the rat erythrocyte membrane.膳食锌缺乏对大鼠红细胞膜脂质成分的影响。
Lipids. 1991 Jun;26(6):459-66. doi: 10.1007/BF02536073.