Castillo-Fenoy A, Valère P E, Tricot R
Arch Mal Coeur Vaiss. 1978 Mar;71(3):334-9.
The electrical activity of the sino-atrial node has been recorded in the dog through a thoracotomy and using both unipolar and bipolar electrodes. Amiodarone was used to establish that the pre-artial potential which was registered was indeed originating in the sinus, as it allowed us to produce various degrees of sino-atrial block in a reliable and reproducable manner. The fact that the sinus potential can be recorded in the presence of intermittent abnormalities of the surface P wave suggests that the abnormalities may be associated with intra-sinus displacement of the pacemaker and not with ectopic depolarisation of the atrium.
通过开胸手术并使用单极和双极电极,已在犬身上记录到窦房结的电活动。使用胺碘酮来确定所记录的心房前电位确实起源于窦房结,因为它使我们能够以可靠且可重复的方式产生不同程度的窦房传导阻滞。在体表P波存在间歇性异常的情况下仍能记录到窦房结电位,这一事实表明这些异常可能与起搏器在窦房结内的移位有关,而非心房的异位去极化。