局部心肌壁增厚对硝酸甘油的反应。主动脉冠状动脉搭桥手术心肌反应的一个预测指标。

Regional myocardial wall thickening response to nitroglycerin. A predictor of myocardial response to aortocoronary bypass surgery.

作者信息

Chesebro J H, Ritman E L, Frye R L, Smith H C, Rutherford B D, Fulton R E, Pluth J R, Barnhorst D A

出版信息

Circulation. 1978 May;57(5):952-7. doi: 10.1161/01.cir.57.5.952.

DOI:10.1161/01.cir.57.5.952

Abstract

The peak rate of systolic wall thickening (p +/- dTw/dt) in regions of the left ventricle (LV) was determined preoperatively by biplane roentgen videometry in 18 patients before and after sublingual administration of nitroglycerin (NTG) and 3-23 months (median 12) after aortocoronary bypass surgery. The regional LV response to NTG was a reliable predictor for postoperative improvement in regional wall dynamics after successful aortocoronary bypass grafting. The ejection fraction response to NTG or surgery will not predict the regional myocardial response to NTG or surgery, nor will the regional response predict the global response. Subendocardial myocardial infarction is another cause of unimproved regional myocardial function after NTG and aortocoronary bypass surgery.

摘要

18例患者在舌下含服硝酸甘油（NTG）前后以及主动脉冠状动脉搭桥手术后3 - 23个月（中位数12个月），通过双平面X线视频测量法术前测定左心室（LV）区域的收缩期壁增厚峰值速率（p +/- dTw/dt）。左心室对NTG的区域反应是成功进行主动脉冠状动脉搭桥移植术后区域壁动力学术后改善的可靠预测指标。对NTG或手术的射血分数反应无法预测对NTG或手术的区域心肌反应，区域反应也无法预测整体反应。心内膜下心肌梗死是NTG和主动脉冠状动脉搭桥手术后区域心肌功能未改善的另一个原因。