脑膜炎奈瑟菌对磺胺嘧啶钠和夫西地酸钠的体外敏感性比较。
Comparison of susceptibility of Neisseria meningitidis to sodium sulphadiazine and sodium fusidate in vitro.
作者信息
Miles R S, Moyes A
出版信息
J Clin Pathol. 1978 Apr;31(4):355-8. doi: 10.1136/jcp.31.4.355.
Abstract
Out of 100 strains of meningococci examined 62 were resistant to 1 mg/l or more of sodium sulphadiazine, including 82% of group W135 strains and 69% of group B strains. All strains were sensitive in vitro to 0.5 mg/l of sodium fusidate. Sodium fusidate should be considered as a chemoprophylactic agent for those who may be at risk of meningococcal disease.
摘要
在检测的100株脑膜炎球菌中，有62株对1毫克/升或更高浓度的磺胺嘧啶钠耐药，其中包括82%的W135群菌株和69%的B群菌株。所有菌株在体外对0.5毫克/升的夫西地酸钠敏感。对于有患脑膜炎球菌病风险的人群，应考虑将夫西地酸钠作为化学预防剂。
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