1966年至1971年间分离出的脑膜炎球菌的血清型及磺胺敏感性
Serotype and sulphonamide sensitivity of meningococci isolated from 1966 to 1971.
作者信息
Abbott J D, Graves J F
出版信息
J Clin Pathol. 1972 Jun;25(6):528-30. doi: 10.1136/jcp.25.6.528.
Abstract
From 1966 to 1971, 298 cultures of meningococci from clinical material (cerebrospinal fluid or blood) were examined. Eighty-nine cultures were from the Manchester area and the remainder from other parts of England or Northern Ireland. Five per cent of strains were group A, 57% group B, and 31% group C; 6% were untypable. Eighteen strains (6%) had an MIC of 6.4 mug/ml or more of sodium sulphadiazine and 10 of these (3.5%) an MIC of 50 to 100 mug/ml. The incidence of sulphonamide resistance was higher in group A strains than in group B or group C strains.
摘要
1966年至1971年期间，对298份来自临床材料（脑脊液或血液）的脑膜炎球菌培养物进行了检查。89份培养物来自曼彻斯特地区，其余来自英格兰其他地区或北爱尔兰。5%的菌株为A群，57%为B群，31%为C群；6%无法分型。18株（6%）对磺胺嘧啶钠的最低抑菌浓度（MIC）为6.4μg/ml或更高，其中10株（3.5%）的MIC为50至100μg/ml。A群菌株中磺胺耐药的发生率高于B群或C群菌株。
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