Mutagenic evaluation of clonazepam using in vitro and in vivo bacterial tests.
作者信息
Matsubara E, Arisawa M, Maruyama H B
出版信息
Mutat Res. 1978 Mar;57(1):17-26. doi: 10.1016/0027-5107(78)90230-0.
PMID:417244
Abstract
The mutagenicity of an anti-epileptic drug, clonazepam, and its metabolites was studied by three repair (rec, pol and uvr) assays and reversion (Ames') tests. No detectable induction of mutation could be found in any tests by them per se or via metabolism in rat and mouse.
摘要
Zotero 插件