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抗原-抗体复合物与风团及皮肤红斑反应。

Antigen-antibody complexes and the weal and erythema skin responses.

作者信息

Farah F S, Kurban A K

出版信息

Immunology. 1968 Apr;14(4):569-73.

PMID:4172529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1409390/
Abstract

The smallest amount of purified antibody capable of positive weal and erythema response is of the order of 4 μg N. Antigen—antibody complexes are capable of producing specific weal and erythema reactions with antigen—antibody ratio of 1:1 or above. In these instances antibodies occupied at one or both sites are responsible for this response. Preformed antigen—antibody complexes are capable of mediating this response.

摘要

能够引发阳性风团和红斑反应的纯化抗体的最小量约为4μg氮。抗原-抗体复合物在抗原-抗体比例为1:1或更高时能够产生特异性风团和红斑反应。在这些情况下,占据一个或两个位点的抗体是这种反应的原因。预先形成的抗原-抗体复合物能够介导这种反应。

相似文献

1
Antigen-antibody complexes and the weal and erythema skin responses.抗原-抗体复合物与风团及皮肤红斑反应。
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本文引用的文献

1
The relation between molecular weight of antigen and ability to elicit passive cutaneous anaphylaxis.抗原分子量与引发被动皮肤过敏反应能力之间的关系。
Immunology. 1962 Jan;5(1):1-10.
2
THE EFFECTS OF HEAT ON ANTIBODY ACTIVITY.热对抗体活性的影响。
J Immunol. 1964 Aug;93:300-4.
3
REAGINS.反应素
Br Med Bull. 1963 Sep;19:235-40. doi: 10.1093/oxfordjournals.bmb.a070063.
4
A possible correlation between the minimum sensitizing dose of antibody in passive anaphylaxis and the molecular weight of the antigen.被动过敏反应中抗体的最小致敏剂量与抗原分子量之间可能存在的相关性。
J Immunol. 1960 Dec;85:588-90.
5
The biological activity of soluble antigen-antibody complexes. II. Physical properties of soluble complexes having skin-irritating activity.可溶性抗原-抗体复合物的生物学活性。II. 具有皮肤刺激活性的可溶性复合物的物理性质。
J Exp Med. 1959 Feb 1;109(2):127-43. doi: 10.1084/jem.109.2.127.
6
Biological activity of soluble antigen-antibody complexes. I. Skin reactive properties.可溶性抗原-抗体复合物的生物学活性。I. 皮肤反应特性。
Proc Soc Exp Biol Med. 1958 Mar;97(3):635-8. doi: 10.3181/00379727-97-23829.
7
Studies on the antibodies in rabbit antisera responsible for sensitization of human skin. I. The role of impurities in crystalline egg albumin in stimulating the production of skin-sensitizing antibody.关于兔抗血清中引起人皮肤致敏的抗体的研究。I. 结晶卵清蛋白中的杂质在刺激皮肤致敏抗体产生中的作用。
J Exp Med. 1953 Jun;97(6):821-44. doi: 10.1084/jem.97.6.821.