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[About the comparison of closely related species chimpanzee-man and fox-dog in respect of the possibility of xenotransplantation (author's transl)].

作者信息

Prange C H, Kessler M, Marklein G, Kliems G

出版信息

Res Exp Med (Berl). 1978 Jan 30;172(1):33-43. doi: 10.1007/BF01851063.

Abstract

Although the transplant combinations chimpanzee-man on one hand and fox-dog on the other hand have nearly the same phylogenetic development within their zoological family, it is not quite correct to compare the immunological reactions and patterns of rejection of xenogeneic transplants within these systems. The differences in immunochemistry of serum proteins between these two systems confirm that chimpanzee and man are more closely related than fox and dog concerning their genetic disparity. This and other mentioned examples demonstrate the possibility of obtaining qualitative informations of genetic constellations between xenogeneic species combinations by comparing immunochemistry of serum proteins.

摘要

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