Griffiths C T, Fuller A F
Surg Clin North Am. 1978 Feb;58(1):131-42. doi: 10.1016/s0039-6109(16)41440-4.
We have presented the background and rationale for initiating a program of intensive surgical and chemotherapeutic management of advanced ovarian cancer. Our goal of excising all tumor masses larger than 1.5 cm in diameter has been explained and our operative approach described. The necessity for nutritional support has been emphasized. Preliminary results among patients with Stage III disease treated by optimal operation and Adriamycin-cyclophosphamide chemotherapy are encouraging. Aggressive operations have been unsuccessful when employed as secondary treatment. The single most important contraindication to extensive operation is the inability to initiate effective chemotherapy in the postoperative period.
我们已经介绍了启动晚期卵巢癌强化手术及化疗管理项目的背景和基本原理。我们切除所有直径大于1.5厘米肿瘤肿块的目标已作解释，手术方法也已描述。营养支持的必要性已得到强调。通过最佳手术及阿霉素-环磷酰胺化疗治疗的Ⅲ期疾病患者的初步结果令人鼓舞。作为二线治疗采用积极手术未获成功。广泛手术的唯一最重要禁忌证是术后无法启动有效化疗。
