Böhland W, Sauer D
Z Exp Chir. 1978;11(1):32-6.
After discussing a model of infection in mice and the possibility of active immunization against pyocyanic pseudomonas, the authors describe the effect of a lipid-protein-complex achieved from isolated burnt mouse skin on pseudomonas infection. First results showed that sublethal amounts of that complex at otherwise less pathogenic suspension of pseudomonas cause a lethality of 100 per cent. This effect can partially inhibited by application of antitoxic IgG. The lethal course was not primarily caused by the infection but by the above mentioned complex which significantly lowers the resistance against pyocyanic pseudomonas.
在讨论了小鼠感染模型以及针对绿脓假单胞菌进行主动免疫的可能性之后，作者描述了从烧伤小鼠分离皮肤中提取的脂蛋白复合物对假单胞菌感染的影响。初步结果表明，在致病性较低的假单胞菌悬液中，亚致死剂量的该复合物可导致100%的致死率。应用抗毒素IgG可部分抑制这种作用。致死过程并非主要由感染引起，而是由上述复合物导致的，该复合物显著降低了对绿脓假单胞菌的抵抗力。
