Russ J E, DeWys W D
Arch Intern Med. 1978 May;138(5):799-800.
A complete remission of widely metastatic bladder carcinoma was obtained with chemotherapy in a 41-year-old man. Severe persistent anorexia led to a 33% weight loss. The anorexia correlated with an elevated sucrose recognition threshold. Following 16 days of intravenous hyperalimentation, taste sensation returned to normal, anorectic symptoms cleared, and weight gain and positive nitrogen balance resulted. There was no stimulation of tumor growth. Restoration of nutritional deficits with intravenous hyperalimentation can improve taste function and appetite so that adequate oral alimentation can be tolerated.
一名41岁男性患者通过化疗实现了广泛转移的膀胱癌完全缓解。严重且持续的厌食导致体重减轻了33%。这种厌食与蔗糖识别阈值升高相关。在进行了16天的静脉高营养治疗后,味觉恢复正常,厌食症状消除,体重增加且出现正氮平衡。未观察到肿瘤生长受到刺激。通过静脉高营养治疗纠正营养缺乏可改善味觉功能和食欲,从而使患者能够耐受充足的经口营养摄入。