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[重度神经性厌食症的临床研究:静脉高营养疗法的作用]

[Clinical study of severe anorexia nervosa: the role of intravenous hyperalimentation therapy].

作者信息

Denda K, Kitagawa N, Shimanaka S

机构信息

Department of Psychiatry, Hokkaido, University School of Medicine.

出版信息

Seishin Shinkeigaku Zasshi. 1997;99(4):198-214.

PMID:9170982
Abstract

In order to understand the psychopathology of severe anorexia nervosa (AN), and determine appropriate therapeutic approaches, a clinical study was conducted on 13 patients with severe AN who were hospitalized and were treated with intravenous hyperalimentation (IVH). The patients were divided into three types based on their clinical symptoms and initiating factors: Type I (Restricting Type; "Non-dieters"), Type II (Restricting Type: "Dieters"). Type III (Binge-eating/Purging Type). The clinical features of each type were evaluated. Based on this evaluation, the basic approach and the role of IVH in the treatment of each type are described as follows. Type I: The patients experience loss of appetite and subsequently, suffer involuntary weight loss as a result of psychological or physical stresses at school and/or home. Since the patients do not intentionally restrict food intake, they cannot explain the loss of appetite. The age at onset of this type is the youngest among the three groups. The patients are introverted, passive and not good at expressing their emotions. Therefore, it is often difficult to deepen the emotional commitment further. It is possible to understand the pathology of Type I through the psychosomatic model. IVH therapy promotes benign regression for Type I patients, so that the mother-child relationship may be restored. As the therapeutic progress, the mother child relationship occasionally become ambivalent. In such a case, it is important for the treatment team to support independent activities of the patients. Type II: The patients lose weight by intentionally restricting necessary food intake for reasons such as beauty or sports. Any experience of failure in studies or sports or trouble in complex personal relations can trigger the onset of AN. Weight loss is looked as a great achievement, whereas weight gain is recognized as a serious failure of self-control. Since type II patients understand the necessity of receiving treatment, it is possible to establish a trusting relationship during therapy. Their prognosis is generally good. The psychotherapeutic approach for Type II patients is most effective in the context of a weight gain program utilizing behavior therapy. It is important for the therapist to integrate psychological approach with physiological approach using IVH, and to modify cognitive distortion and body image disturbance. Type III: The patients have regularly engaged in binge eating or purging (or both) in the progress of AN. But as they intensely fear becoming fat, they refuse to maintain a minimally normal body weight. Therefore, they exhibit recurrently inappropriate compensatory behavior in order to prevent weight gain. In the therapeutic sessions, they often become ambivalent and unstable, showing dissatisfaction and reacting strongly against their therapists. The age at onset is the oldest of the three types. The prognosis is not good in many cases. IVH therapy may be required only in life-threatening situation for Type III patients. And severe bulimic patients may require sufficient drug treatment. The patients should be trained for interpersonal relationships at the day care unit or the occupational therapy unit. And they should be encouraged to adapt to real life.

摘要

为了解重度神经性厌食症(AN)的精神病理学并确定合适的治疗方法,对13例因重度AN住院并接受静脉高营养(IVH)治疗的患者进行了一项临床研究。根据患者的临床症状和发病因素将其分为三种类型:I型(限制型;“非节食者”)、II型(限制型:“节食者”)、III型(暴饮暴食/清除型)。对每种类型的临床特征进行了评估。基于该评估,如下描述IVH在每种类型治疗中的基本方法和作用。I型:患者食欲不振,随后由于学校和/或家庭中的心理或身体压力而出现非自愿体重减轻。由于患者并非故意限制食物摄入,他们无法解释食欲不振的原因。该类型的发病年龄在三组中是最小的。患者性格内向、被动,不善于表达自己的情绪。因此,通常很难进一步深化情感投入。通过心身模型可以理解I型的病理。IVH治疗可促进I型患者的良性康复,从而恢复母子关系。随着治疗进展,母子关系偶尔会变得矛盾。在这种情况下,治疗团队支持患者的独立活动很重要。II型:患者因追求美或运动等原因故意限制必要的食物摄入量以减轻体重。学习或运动中的任何失败经历或复杂人际关系中的问题都可能引发AN的发作。体重减轻被视为一项巨大成就,而体重增加则被认为是自我控制的严重失败。由于II型患者理解接受治疗的必要性,因此在治疗期间有可能建立信任关系。他们的预后通常良好。II型患者的心理治疗方法在利用行为疗法的体重增加计划背景下最为有效。治疗师将心理方法与使用IVH的生理方法相结合,并纠正认知扭曲和身体形象障碍很重要。III型:患者在AN病程中经常有暴饮暴食或清除(或两者兼有)行为。但由于他们极度害怕发胖,他们拒绝维持最低正常体重。因此,他们反复表现出不适当的代偿行为以防止体重增加。在治疗过程中,他们常常变得矛盾和不稳定,表现出不满并强烈反抗治疗师。发病年龄在三种类型中是最大的。在许多情况下预后不佳。III型患者仅在危及生命的情况下可能需要IVH治疗。严重的贪食症患者可能需要充分的药物治疗。患者应在日托单位或职业治疗单位接受人际关系培训。并且应鼓励他们适应现实生活。

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