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肺出血肾炎综合征的免疫学方面

Immunological aspects of Goodpasture's syndrome.

作者信息

Markowitz A S, Battifora H A, Schwartz F, Aseron C

出版信息

Clin Exp Immunol. 1968 Jul;3(6):585-91.

PMID:4178233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1578947/
Abstract

A typical case of Goodpasture's syndrome is reported. Immunofluorescence studies disclosed linear deposition of γ- and β-globulins on the glomerular and pulmonary basement membranes. The possibility that this indicates a common pathogenesis is suggested by these findings and an hypothesis in support of this view is presented.

摘要

报告了一例典型的古德帕斯丘综合征病例。免疫荧光研究显示γ球蛋白和β球蛋白在肾小球和肺基底膜上呈线性沉积。这些发现提示了这可能表明存在共同发病机制,并提出了支持这一观点的假说。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/00639770ea96/clinexpimmunol00349-0124-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/c97b4b4fcac0/clinexpimmunol00349-0121-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/44edaa2dc0e7/clinexpimmunol00349-0122-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/ec105b978d6f/clinexpimmunol00349-0123-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/a916bd135803/clinexpimmunol00349-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/00639770ea96/clinexpimmunol00349-0124-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/c97b4b4fcac0/clinexpimmunol00349-0121-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/44edaa2dc0e7/clinexpimmunol00349-0122-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/ec105b978d6f/clinexpimmunol00349-0123-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/a916bd135803/clinexpimmunol00349-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ba/1578947/00639770ea96/clinexpimmunol00349-0124-b.jpg

相似文献

1
Immunological aspects of Goodpasture's syndrome.肺出血肾炎综合征的免疫学方面
Clin Exp Immunol. 1968 Jul;3(6):585-91.
2
Immunohistology of the lung in Goodpasture's syndrome.肺出血肾炎综合征患者肺部的免疫组织学表现。
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Nouv Presse Med. 1972 Nov 18;1(41):2743-6.
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引用本文的文献

1
Immunohistological study of human lungs by immunoperoxidase technique.采用免疫过氧化物酶技术对人肺进行免疫组织学研究。
J Clin Pathol. 1982 Feb;35(2):144-50. doi: 10.1136/jcp.35.2.144.
2
Goodpasture's syndrome: treatment with plasmapheresis, immunosuppression, and anticoagulation.肺出血肾炎综合征:采用血浆置换、免疫抑制及抗凝治疗。
Arch Dis Child. 1983 Sep;58(9):697-702. doi: 10.1136/adc.58.9.697.
3
Pathogenesis of nephrosis.肾病的发病机制。

本文引用的文献

1
Pulmonary lesions produced by nephrotoxic anti-placenta serum.肾毒性抗胎盘血清所致的肺部病变
Int Arch Allergy Appl Immunol. 1962;20:298-305. doi: 10.1159/000229268.
2
DEPOSITION OF AUTOLOGOUS GAMMA GLOBULIN IN KIDNEYS OF RATS WITH NEPHROTIC RENAL DISEASE OF VARIOUS ETIOLOGIES.不同病因的肾病大鼠肾脏中自体γ球蛋白的沉积
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PULMONARY HEMORRHAGE AND GLOMERULONEPHRITIS. REPORT OS SIX CASES AND STUDY OF THE RENAL LESION BY THE FLUORESCENT ANTIBODY TECHNIQUE AND ELECTRON MICROSCOPY.肺出血与肾小球肾炎。六例报告及应用荧光抗体技术和电子显微镜对肾脏病变的研究
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Goodpasture's syndrome. Treatment with nephrectomy and renal transplantation.古德帕斯彻综合征。肾切除术及肾移植治疗。
Arch Surg. 1971 Aug;103(2):283-9. doi: 10.1001/archsurg.1971.01350080199031.
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Bright's disease today: the pathogenesis and treatment of glomerulonephritis. 3.当今的布赖特氏病:肾小球肾炎的发病机制与治疗。3.
Br Med J. 1972 Oct 28;4(5834):217-20. doi: 10.1136/bmj.4.5834.217.
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[Immunologic lung diseases due to circulating antibodies (author's transl)].循环抗体所致的免疫性肺部疾病(作者译)
Klin Wochenschr. 1974 Mar 15;52(10):466-73. doi: 10.1007/BF01468534.
7
Immunologic studies concerning the pulmonary lesions in Goodpasture's syndrome.关于古德帕斯彻综合征肺部病变的免疫学研究。
Am J Pathol. 1969 Feb;54(2):293-305.
Ann Intern Med. 1965 May;62:920-38. doi: 10.7326/0003-4819-62-5-920.
4
GOODPASTURE'S SYNDROME: A CLINICOPATHOLOGIC ENTITY.古德帕斯彻综合征:一种临床病理实体。
Am J Med. 1964 Sep;37:424-44. doi: 10.1016/0002-9343(64)90199-8.
5
[Pneumopathy induced in rat by nephrotoxic sera (rabbit anti-rat-kidney and anti-rat-lung sera)].[肾毒性血清(兔抗大鼠肾和抗大鼠肺血清)诱导大鼠产生的肺病]
Rev Assoc Med Bras. 1960 Jun;6:185-96.
6
Nephrotoxic serum nephritis in rats. I. Distribution and specificity of the antigen responsible for the production of nephrotoxic antibodies.大鼠肾毒性血清肾炎。I. 负责产生肾毒性抗体的抗原的分布及特异性。
J Exp Med. 1956 Oct 1;104(4):467-85. doi: 10.1084/jem.104.4.467.
7
The invitro purification of tissue localizing antibodies.组织定位抗体的体外纯化
J Immunol. 1953 Jul;71(1):1-5.
8
Goodpasture's syndrome. Prolonged survival with chronic hemodialysis.古德帕斯彻综合征。经长期慢性血液透析实现长期存活。
Arch Intern Med. 1966 May;117(5):643-7. doi: 10.1001/archinte.117.5.643.
9
Streptococcal related glomerulonephritis. II. Glomerulonephritis in rhesus monkeys immunologically induced both actively and passively with a soluble fraction from human glomeruli.链球菌相关性肾小球肾炎。II. 用来自人肾小球的可溶性组分主动和被动免疫诱导恒河猴发生的肾小球肾炎。
J Immunol. 1967 Jan;98(1):161-70.
10
Immunofluorescence studies in a case of Goodpasture's syndrome.一例肺出血肾炎综合征的免疫荧光研究。
JAMA. 1965 Nov 22;194(8):914-6.