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心脏及其他器官提取物与用A组链球菌免疫的动物血清的反应。

The reaction of heart and other organ extracts with the sera of animals immunized with group A streptococci.

作者信息

Lyampert I M, Borodiyuk N A, Ugryumova G A

出版信息

Immunology. 1968 Dec;15(6):845-54.

Abstract

Extracts of guinea-pig skeletal muscle, heart, kidney and liver tissues contain soluble antigens which react in gel precipitation and immunoelectrophoresis with sera of animals immunized with group A streptococci, and with γ-globulin preparations obtained from these sera. These are specific immunological reactions. The antigens in extracts of heart tissue and other organs are proteins. They are cross-reactive antigens since absorption of sera with homologous strains of streptococci abolishes these reactions.

摘要

豚鼠骨骼肌、心脏、肾脏和肝脏组织的提取物含有可溶性抗原,这些抗原在凝胶沉淀和免疫电泳中与用A组链球菌免疫的动物血清以及从这些血清中获得的γ-球蛋白制剂发生反应。这些是特异性免疫反应。心脏组织和其他器官提取物中的抗原是蛋白质。它们是交叉反应性抗原,因为用同源链球菌菌株吸收血清会消除这些反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/507a/1409493/d7f76b056f3b/immunology00395-0070-a.jpg

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