Fournier M, Orgiazzi J, Magnon-Pujo B, Quintana J, Mornex R
Ann Endocrinol (Paris). 1978;39(1):59-60.
The responses of TSH, T3 and T4 to intramuscular administration of 2 mg of TRH were compared in the same subjects to those observed after intravenous injection of 200 microgram of TRH. In 12 normal subjects the TSH and T3 peaks were significantly higher after intramuscular injection. There was no difference in T4 levels. In 15 patients: 5 toxic adenomas after surgery and 10 Graves' disease after treatment the results were comparable for TSH and T3 by the two routes.
在同一受试者中,比较了肌肉注射2mg促甲状腺激素释放激素(TRH)后促甲状腺激素(TSH)、三碘甲状腺原氨酸(T3)和甲状腺素(T4)的反应与静脉注射200微克TRH后的反应。在12名正常受试者中,肌肉注射后TSH和T3的峰值显著更高。T4水平没有差异。在15名患者中:5名术后毒性腺瘤患者和10名治疗后的格雷夫斯病患者,两种给药途径的TSH和T3结果具有可比性。