Lorcy Y, Heim J, Auvray E, Allannic H
Ann Endocrinol (Paris). 1979 Jul-Aug;40(4):441-2.
Serum concentrations of Thyroxine (T4), triiodothyronine (T3) free thyroxine index (F.T.I.) and TSH response to TRH were evaluated in 55 Graves' diseases treated by Carbimazole. There is a good correlation between serum thyroid hormones and clinical state: 83,7% for T4; 79,5% for T3; on the other hand there is a discrepancy between T3 and T4 in many cases and between delta TSH and T4 (47%) or T3 (46%). The decrease of T4 occurs before that of T3: 46,6% normal at the 4th month and 72,5% at the 9th month for T4 against 41% and 50% for T3. At the end of the treatment 96,4% of patients are clinically normal but 20% of them remain with T3 and T4 values above normal.
对55例接受卡比马唑治疗的格雷夫斯病患者的血清甲状腺素（T4）、三碘甲状腺原氨酸（T3）、游离甲状腺素指数（F.T.I.）以及促甲状腺激素（TSH）对促甲状腺激素释放激素（TRH）的反应进行了评估。血清甲状腺激素与临床状态之间存在良好的相关性：T4为83.7%；T3为79.5%；另一方面，在许多情况下，T3与T4之间以及促甲状腺激素变化量（ΔTSH）与T4（47%）或T3（46%）之间存在差异。T4的下降先于T3：治疗第4个月时T4正常的比例为46.6%，第9个月时为72.5%，而T3在第4个月和第9个月时正常的比例分别为41%和50%。治疗结束时，96.4%的患者临床症状正常，但其中20%的患者T3和T4值仍高于正常水平。
