Wells C E
Res Publ Assoc Res Nerv Ment Dis. 1979;57:281-305.
Our best hope of helping patients who appear to be demented lies in the painstaking diagnostic evaluation of each such patient whom the physician encounters. The first step is to separate out those patients who appear to have organic dementias but in fact do not. These pseudodemented patients, i.e., patients with functional psychiatric disorders mimicking dementia, often have an excellent prognosis. Next, in those patients with diffuse organic dysfunction, a diligent search must be made for those disorders that are amenable to specific therapy. Good evidence is available to demonstrate that thorough diagnostic evaluation pays off in the identification of a significant proportion of treatable disease. Even when no treatable disease can be identified, treatment of coexisting medical and physical problems, environmental manipulation, and pharmacologic therapy can do much to alleviate the patient's plight.
帮助那些看似患有痴呆症的患者,我们最大的希望在于医生对每一位遇到的此类患者进行细致的诊断评估。第一步是区分出那些看似患有器质性痴呆但实际上并非如此的患者。这些假性痴呆患者,即患有模仿痴呆的功能性精神障碍的患者,通常预后良好。接下来,对于那些患有弥漫性器质性功能障碍的患者,必须努力寻找那些适合特定治疗的疾病。有充分的证据表明,全面的诊断评估在识别相当一部分可治疗疾病方面是有成效的。即使无法识别出可治疗的疾病,治疗并存的医疗和身体问题、调整环境以及药物治疗也能在很大程度上缓解患者的困境。