Lehninger F W, Ravindran V L, Stewart J T
Geropsychiatry Section, Bay Pines VA Medical Center, Tampa, USA.
Geriatrics. 1998 Apr;53(4):55-6, 66-8, 71-5.
Psychiatric and behavioral problems are present in most patients with dementia and are usually the clinician's main focus of management. Differential diagnosis of these problems can be challenging, but the effort is essential for planning appropriate therapy. Pharmacologic interventions are available for treatment of depression, agitation, aggression, psychotic symptoms, wandering, and sleep disorders. Given the less than favorable risk-benefit ratio of most psychotropic drugs in the population of older patients with dementia, the importance of nonpharmacologic strategies and limiting treatment goals should not be overlooked.
大多数痴呆患者存在精神和行为问题，这些问题通常是临床医生管理的主要重点。对这些问题进行鉴别诊断可能具有挑战性，但这一努力对于制定适当的治疗方案至关重要。有药物干预措施可用于治疗抑郁症、激越、攻击行为、精神病性症状、徘徊和睡眠障碍。鉴于大多数精神药物在老年痴呆患者人群中的风险效益比不尽人意，非药物策略的重要性以及限制治疗目标不应被忽视。
