Treatment of anaerobic infections with metronidazole.
作者信息
Christensson B, Hedström S A, Ursing B
出版信息
Scand J Infect Dis. 1979;11(1):69-72. doi: 10.3109/inf.1979.11.issue-1.11.
PMID:419371
Abstract
Metronidazole (Flagl), a compound widely used in man with minimal side-effects, has been used in the treatment of anaerobic infections caused by Bacteroides fragilis and other Bacteroides species. Seven patients were treated and all were restored to full health. Four of them did not respond to lincomycin or clindamycin which so far have been the drugs of choice against anaerobic infections. The reasons for the good results during metronidazole therapy such as the good penetration through the blood/brain barrier and into abscess cavities are discussed.
摘要
相似文献
1
Treatment of anaerobic infections with metronidazole.
Scand J Infect Dis. 1979;11(1):69-72. doi: 10.3109/inf.1979.11.issue-1.11.
2
Successful treatment of Bacteroides bacteraemia with metronidazole, after failure with clindamycin and lincomycin.
J Antimicrob Chemother. 1977 May;3(3):233-7. doi: 10.1093/jac/3.3.233.
3
Metronidazole treatment of Bacteroides fragilis infections.
Am J Med Sci. 1980 Nov-Dec;280(3):143-9. doi: 10.1097/00000441-198011000-00002.
4
Therapy for infections due to anaerobic bacteria: an overview.厌氧菌感染的治疗：概述
J Infect Dis. 1977 Mar;135 Suppl:S25-9. doi: 10.1093/infdis/135.supplement.s25.
5
Letter: Bacteroides infections.
Lancet. 1973 Nov 10;2(7837):1081-2. doi: 10.1016/s0140-6736(73)92680-9.
6
A comparison of metronidazole and clindamycin for the treatment of intra-abdominal anaerobic infection: a multicentre trial.
J Antimicrob Chemother. 1982 Jul;10(1):57-66. doi: 10.1093/jac/10.1.57.
7
Metronidazole therapy of anaerobic bacteremia, meningitis, and brain abscess.
Arch Intern Med. 1979 Feb;139(2):167-9.
8
Relative antibacterial efficacy of clindamycin and metronidazole against Bacteroides fragilis in vitro and in experimentally infected mice.
Chemotherapy. 1985;31(4):297-303. doi: 10.1159/000238351.
9
Therapeutic efficacy of moxifloxacin, a new quinolone, in the treatment of experimental intra-abdominal abscesses induced by Bacteroides fragilis in mice.新型喹诺酮类药物莫西沙星对小鼠脆弱拟杆菌所致实验性腹腔脓肿的治疗效果
Chemotherapy. 2004 Jun;50(2):76-80. doi: 10.1159/000077806.
10
Therapeutic efficacy and pharmacokinetic properties of rifampicin in a Bacteroides fragilis intra-abdominal abscess.
J Antimicrob Chemother. 1984 Dec;14(6):633-40. doi: 10.1093/jac/14.6.633.
Zotero 插件