Cameron J L, Mehigan D, Zuidema G D
Surg Gynecol Obstet. 1979 Feb;148(2):206-8.
A prospective randomized clinical trial was carried out to evaluate the efficacy of atropine in the treatment of acute pancreatitis. Fifty-one patients with elevated amylase levels, and with the clinical signs and symptoms of acute pancreatitis, were included in the study. All were treated with fluids intravenously and analgesics, and a nasogastric tube if needed. In addition, on a random basis, 19 were given atropine intramuscularly and 32 were not. The clinical courses of the two groups of patients did not differ significantly.
开展了一项前瞻性随机临床试验,以评估阿托品治疗急性胰腺炎的疗效。该研究纳入了51例淀粉酶水平升高且有急性胰腺炎临床体征和症状的患者。所有患者均接受静脉补液和镇痛药治疗,必要时放置鼻胃管。此外,随机抽取19例患者肌肉注射阿托品,32例未注射。两组患者的临床病程无显著差异。