Rozee K R, Easterbrook K B
Appl Microbiol. 1970 Jun;19(6):997-1000. doi: 10.1128/am.19.6.997-1000.1970.
A continuous cell line of rhesus monkey kidney cells, LLC-MK(2), was infected with reovirus type 1 (Lang). The cells were freeze-etched as a method for observing the structural details of the reovirus-induced cytoplasmic inclusion. Information on maturation may be obtained by preparing infected cells for electron microscopy by freeze-etching.
将恒河猴肾细胞连续细胞系LLC-MK(2)用1型呼肠孤病毒（Lang株）感染。通过冷冻蚀刻处理细胞，以此作为观察呼肠孤病毒诱导的细胞质内含物结构细节的一种方法。关于病毒成熟的信息可通过冷冻蚀刻法制备用于电子显微镜观察的感染细胞来获取。
