Knoch H G, Köbernick H, Ernst F D
Zentralbl Chir. 1979;104(1):58-62.
Single cases of genuine colon rectum polypi, histologically adenomatous, adeno-villous and villous tumours have been treated with cryosurgery.
Relapses after polyectomy showing malignant degeneration; malignantly degenerated polypi, treatment of the basis of sessile lesions; sessile polypi up to 1 cm in diameter; extensive polyposis--polyposis of the rectum. After an initial regression of the polypous changes growth can be stated and quickly developing degenration leading to the formation of a carcinoma of the rectum and to stenoses of the lumen. It was only partially possible to clarify the cause of the growth in animal experiments. Primary application of low temperatures in polyposis recti and in primarily malignant degenerated polypi have to be avoided.
单纯的结直肠息肉病例，组织学上为腺瘤性、腺绒毛状和绒毛状肿瘤，已采用冷冻手术治疗。
息肉切除术后复发并显示恶性变；恶性变的息肉，基于无蒂病变的治疗；直径达1厘米的无蒂息肉；广泛性息肉病——直肠息肉病。在息肉样改变初步消退后可观察到生长情况，且快速发展的退变可导致直肠癌形成和管腔狭窄。在动物实验中仅部分阐明了生长原因。必须避免在直肠息肉病和原发性恶性变息肉中首次应用低温。
